Spot® Endoscopic Marker

Spot® Endoscopic Marker

Reintroducing Spot, the trusted tattoo used for over 20 years in over 40 countries worldwide
  • Robust clinical evidence documented through more than 25 peer reviewed published studies and society guidelines
  • Used in more than 5 million cases globally, with no reported adverse events1
Tattooing enables fast and easy identification
  • Tattooing has been shown to reduce OR time by up to 40 minutes2
Tattooing with Spot® is cost effective
  • Tattooing with Spot® is cost effective with dedicated reimbursement
  • Tattooing is reimbursed as a submucosal injection CPT code 45381

Item Numbers:

  • GIS-44 (5 mL syringe)
  • GIS-42 (8 mL syringe)
  • GIS-41 (10 mL syringe)

Download Spot® Reimbursement Guide (PDF)


For any questions or to receive a quote, please contact us.


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Frequently Asked Questions

Spot comes in a pre-filled syringe. Spot 5 mL is packaged in a tube and 8 mL is packaged in a tray. Both are sold in boxes of 10 syringes

5 mL is the original size and is plenty for most patients. 8 mL was created for those patients who may need to be tattooed in more than one location allowing a nurse or tech to pull one syringe without going above the maximum dosage per patient.

Spot is indicated for resection within 30 days; however, in a long term clinical study Spot has been visible in patients for over 10 years.

(citation: Jackson FW. Long-term Visibility of Endoscopic Tattoos Using Sterile Carbon Suspension in a Prefilled Syringe. American Journal of Gastroenterology 2017; 112:S1–S45)

Spot is indicated for surgical localization.

Surgical localization refers to the surgeon’s need to precisely locate an area of interest that was previously identified endoscopically. Endoscopic tattoos placed by the referring gastroenterologist are readily located at the time of surgery, facilitating quicker surgical localization.

(citation: Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg . 2006. 30(4):605–611)

Clinical surveillance refers to a clinician’s choice to monitor, or follow-up with, a patient at future intervals based on practice guidelines. Endoscopic tattoos help ensure the providers identify the same area of interest at each surveillance interval.

To see the only endoscopic marker that is indicated for clinical surveillance and permanent with proven data please visit Spot Ex Endoscopic Tattoo page on this website.

0.5-0.75ml of Spot® should be injected submucosally into four quadrants distal to the lesion of interest. Use a 23 or 25 gauge injection needle at an angle so that the beveled tip of the needle is entirely beneath the mucosa. If the needle is inserted perpendicular to the mucosa, there is a risk of penetrating the serosa and injecting the marker directly into the peritoneal cavity.

Shaking Spot Ex for 15-20 seconds prior to loading the injection needle insures a consistent color throughout injection.

Absolutely! Download the Spot® Reimbursement Guide found on this page.

Please download the Indications for Use (IFU) document to see all Indications, Contraindications and Procedural Risk information.

How to Order



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