Spot® Ex Endoscopic Tattoo

Take The Next Step In The Fight Against Colon Cancer

Expanded indications support adoption of guidelines¹*

  • Spot Ex is indicated for both clinical surveillance and surgical localization²*
  • Spot Ex is permanent,² enabling a lifetime of follow-up procedures

Expedite localization at follow-up procedures³*

  • Spot Ex is easier to find4* because it’s much darker than Spot®5*
  • Tattooing reduces Operating Room (OR) time by up to 40 minutes by improving surgical localization6*
  • Even easier to use Zero-Step Prep™ syringe

Exceedingly cost effective

  • Reimbursement more than covers cost of care (See 2018 CMS Tissue Marking Example)

Item #:

  • Spot Ex Endoscopic Tattoo (Box of 10): GIS-45

*See References tab for full citations.
**Spot Ex is only available for sale in the United States.

Spot Ex helps clinicians take the next step in the fight against colon cancer by providing a lifetime of clinical surveillance for their patients.

  • Spot Ex comes in a pre-filled, pre-assembled syringe with a roll-proof cap to make it even easier and more convenient to use.
  • Spot Ex is sold in boxes of 10 syringes.

How is Spot Ex sold?
Spot Ex comes in a prefilled, pre-assembled, Zero-Step Prep™ syringe with a roll proof cap. Spot Ex is sold in boxes of 10 syringes.

How long is a Spot Ex tattoo visible in the body?
Spot Ex is permanent, affording clinicians a lifetime of follow-up procedures for their patients who are at future risk of colon cancer.

What is Spot Ex for?
Spot Ex is the first and only endoscopic tattoo indicated for both surgical localization and clinical surveillance.

What is clinical surveillance?
Clinical surveillance refers to a clinician’s choice to monitor, or follow-up with, a patient at future intervals based on practice guidelines. Endoscopic tattoos help ensure the providers identify the same area of interest at each surveillance interval.

What is surgical localization?
Surgical localization refers to the surgeon’s need to precisely locate an area of interest that was previously identified endoscopically. Endoscopic tattoos placed by the referring gastroenterologist are readily located at the time of surgery, facilitating quicker surgical localization1.

1. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg . 2006. 30(4):605–611

When should Spot Ex be used?
Download Clinical Uses of Follow-Up Tattoos

Does Spot Ex need to be stored in the Pharmacy?
No. Spot Ex is an FDA-cleared medical device. It can be stored in the procedure room under normal conditions.

How do I store Spot Ex in the procedure room?
Spot Ex can be stored at room temperature for up to two years. For best results, do not store with the syringe tips pointing down.

How do I inject Spot Ex?
0.5-0.75ml of Spot Ex should be injected submucosally into four quadrants distal to the lesion of interest. Use a 23 or 25 gauge injection needle at an angle so that the beveled tip of the needle is entirely beneath the mucosa. If the needle is inserted perpendicular to the mucosa, there is a risk of penetrating the serosa and injecting the marker directly into the peritoneal cavity.
Download the Spot Ex Getting Started Guide

Why do I need to shake Spot Ex?
Shaking Spot Ex vigorously for 15-20 seconds prior to loading the injection needle insures a consistent color throughout injection.

Is tattooing with Spot Ex a reimbursable procedure?
Absolutely! Download the Spot Ex 2018 CMS Reimbursement Guide

Need something else? Call (800) 451-5797 or fill out our online Contact Us form to request more information.

Spot® Ex Endoscopic Tattoo is covered by the following U.S. patent numbers: 6280702, 6599496, and new patent pending.

Why, When, and How to Effectively Tattoo during Colonoscopy Procedures
Proper endoscopic marking during colonoscopy procedures can be a powerful ally in the fight against colon cancer. In this video, Dr. Douglas K. Rex of the Indiana University School of Medicine explains the Why, When and How of effective endoscopic tattooing.

Methods to Inject Endoscopic Tattoo into the Submucosal Space with Dr. Douglas K. Rex
Two methods that can be used to effectively administer endoscopic tattoos into the submucosal space are the direct and bleb techniques. In this video, Dr. Douglas K. Rex of the Indiana University School of Medicine demonstrates how to tattoo using a direct injection technique, and how to tattoo by using a saline bleb.

1. ESGE Clinical Guideline. Colorectal polypectomy and endoscopic mucosal resection (EMR). 2017
2. Spot Ex Indication. Instructions For Use. Rev 02. Jan 2018
3. Easier identification at follow-up procedures as compared to no tattoo.
4. Lee. P., Finding Endoscopic Tattoos: The Impact of Contrast. GI Supply. 2018.
5. Spot Ex Luminosity Lab Results. Northwestern Biological Imaging Facility. Nov 2017
6. Arteaga-Gonzalez I, et. al., The use of preoperative endoscopic tattooing in laparoscopic colorectal cancer surgery for endoscopically advanced tumors: a prospective comparative clinical study. World J Surg . 2006. 30(4):605–611

Give us a call or send an email/fax to our Customer Service team.

Call (800) 451-5797 (8:30am – 5:00pm EST Monday – Friday)

E-mail orders@gi-supply.com

Fax (717) 761-0216